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Rhizomycosis Infection in the Basal Ganglia
Jeyaraj Durai Pandian, MD, DM;
James S. McCarthy, FRACP;
Tony Goldschlager, MBBS;
Thomas Robertson, FRCPA;
Robert D. Henderson, FRACP
Arch Neurol. 2007;64(1):134-135.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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A 24-year-old man presented with a 2-day history of headache, confusion, and left hemiparesis. He was previously in good health, was not immunocompromised, and tested negative for human immunodeficiency virus infection. Magnetic resonance imaging showed a progressive, nonenhancing lesion involving the basal ganglia that extended into the midbrain with mass effect (Figure, A and B). Analysis of a biopsy specimen from the right caudate lobe showed neutrophil infiltration with broad fungal hyphae with irregular branching (Figure, C). A Rhizomucor species was grown on culture. Specific questioning revealed one occasion of intravenous amphetamine use in the week before admission. The patient died despite antifungal therapy with amphotericin B and external ventricular drainage.
Figure appears in full text version.
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Figure. Imaging results (A and B) and microscopic analysis of the biopsy specimen (C) in our . . . [Full Text of this Article]
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