Physicians in the United States, Canada, and Mexico
Physicians with current and valid licenses in the United States, Canada,
or Mexico who read any 3 of the selected continuing medical education (CME)
articles in this issue of Archives of Neurology,
complete the CME Evaluation Form, and fax it to the number or mail it to the
address at the bottom of the CME Evaluation Form are eligible for category
1 CME credit. There is no charge.
The American Medical Association (AMA) is accredited by the Accreditation
Council for Continuing Medical Education to sponsor continuing medical education
for physicians. The AMA designates this educational activity for up to 3 hours
of category 1 CME credit per Archives of Neurology
issue toward the AMA Physician's Recognition Award (PRA). Each physician should
claim only those hours of credit that were actually spent in this educational
activity.
Physicians in Other Countries
Physicians with current and valid licenses in the United States, Mexico,
or Canada are eligible for CME credit even if they live or practice in other
countries. Physicians licensed in other countries are also welcome to participate
in this CME activity. However, the PRA is only available to physicians licensed
in the United States, Canada, or Mexico.
Statement of Educational Purpose
The Archives of Neurology provides new evidence
for the practice of neurology, neurosurgery, and other specialties whose goal
is to improve the neurological health of all people. Original contributions,
neurological reviews, neurology and public health, and history of neurology
are among the categories of articles published, but all contributions receive
a sympathetic reading by the Chief Editor. The journal's editorial board sets
the initial framework for the types of articles published, which is then modified
by feedback from editors, external peer reviewers, authors, and readers. We
are keen to receive submissions from practicing neurologists to provide new
insight for colleagues.
We want our readers to assess each article critically; this CME activity
is active, not passive. Does the article contribute in some way to the practice
of neurology? How could you modify your practice style to incorporate what
you have learned? How can you acquire more information, challenge the authors'
conclusions, or verify what you have read? Which of the articles in each issue
is least helpful in your quest for the best and most applicable evidence?
Earning Credit
To earn 1 hour of category 1 CME credit, you should read any 3 of the CME articles listed and complete the CME Evaluation Form
on the page following the listing of CME articles listed below.
To earn 3 hours of credit,
read all of the articles listed below and complete the
CME Evaluation Form. The CME Evaluation Form must be submitted within 4 weeks
of the issue date. A certificate awarding up to 3 hours of category 1 CME
credit will be faxed or mailed to you; it is then your responsibility to maintain
a record of credit received. Questions about CME credit processing should
be directed to The Blackstone Group; tel: (312) 419-0400, ext 225; fax: (312)
269-1636.
CME Evaluation
One of our goals is to assess continually the needs of our readers so
we may enhance the educational effectiveness of the Archives
of Neurology. To achieve this goal, we need your help. You must complete
the CME Evaluation Form to receive credit.
CME Articles in This Issue of Archives of Neurology
The articles listed below may be read for CME credit.
Age-Related Memory Decline: Current Concepts and Future
Directions (p. 360)
Educational Objective: To review the effects
of age on memory and brain function.
Glutamate Transporters in Neurologic Disease (p. 365)
Educational Objective: To understand the role
of glutamate transporters in neurologic disease.
Evaluation of CSF-tau and CSF-Aß42 as Diagnostic
Markers for Alzheimer Disease (p. 373)
Educational Objective: To learn if there are
useful cerebrospinal fluid biomarkers for Alzheimer disease.
Frequency of Tau Gene Mutations in Non-Alzheimer Dementia (p. 383)
Educational Objective: To determine the frequency
of tau mutations in dementia that are not are a result of vascular or Alzheimer
pathologic conditions.
Ratio of 8-Hydroxyguanine in Intact DNA to Free 8-Hydroxyguanine
Is Increased in Alzheimer Disease Ventricular Cerebrospinal Fluid (p. 392)
Educational Objective: To examine markers of
oxidative stress in cerebrospinal fluid of individuals with Alzheimer disease.
Mild Cognitive Impairment Represents Early-Stage Alzheimer
Disease (p. 397)
Educational Objective: To recognize that mild
cognitive impairment indicates early Alzheimer disease.
Mild Cognitive Impairments Predict Dementia in Nondemented
Elderly Patients (p. 411)
Educational Objective: To realize that global
cognitive impairments, but not memory loss alone, increase the risk of dementia.
Response of Patients With Alzheimer Disease to Rivastigmine
Treatment (p. 417)
Educational Objective: To understand the relationship
between Alzheimer disease progression rate and response to rivastigmine.
Study of Donepezil in Patients With Alzheimer Disease (p. 427)
Educational Objective: To examine the efficacy
and safety of donepezil in Alzheimer disease.
Postmenopausal Estrogen Replacement Therapy and the
Risk of Alzheimer Disease (p. 435)
Educational Objective: To evaluate the relationship
between postmenopausal estrogen replacement therapy and Alzheimer disease.
Amyloid Precursor Protein in Platelets of Patients
With Alzheimer Disease (p. 442)
Educational Objective: To determine whether
acetylcholinesterase inhibitor therapy modifies the ratio of amyloid precursor
protein forms in Alzheimer disease.
A Method for Estimating Progression Rates in Alzheimer
Disease (p. 449)
Educational Objective: To learn whether disease
progression rate in Alzheimer disease can be predicted.
Alterations of Striatal Dopamine Receptor Binding
in Alzheimer Disease Are Associated With Lewy Body Pathology and Antemortem
Psychosis (p. 466)
Educational Objective: To understand the relationship
of altered striatal dopamine receptor binding and Lewy bodies and psychosis
in Alzheimer disease.
Factors Associated With Incident Human Immunodeficiency
Virus–Dementia (p. 473)
Educational Objective: To identify risk factors
for HIV dementia.
The Effect of Brain Atrophy on Cerebral Hypometabolism
in the Visual Variant of Alzheimer Disease (p. 480)
Educational Objective: To understand the significance
of cerebral metabolic lesion distribution in the visual variant of Alzheimer
disease.
Neuronal Cyclooxygenase 2 Expression in the Hippocampal
Formation as a Function of the Clinical Progression of Alzheimer Disease (p. 487)
Educational Objective: To recognize that neuronal
cyclooxygenase 2 may be an indicator of progression in Alzheimer disease.
Frontal Lobe Hypometabolism Predicts Cognitive Decline
in Patients With Lacunar Infarcts (p. 493)
Educational Objective: To learn that cognitive
decline with lacunes may reflect the neuropathology of subcortical frontal
circuits.
Physical Activity and Risk of Cognitive Impairment
and Dementia in Elderly Persons (p. 498)
Educational Objective: To realize that regular
physical activity may protect elderly people from dementia.
Dementia With Lewy Bodies Studied With Positron Emission
Tomography (p. 505)
Educational Objective: To evaluate the role
of positron emission tomography in the diagnosis of dementia with Lewy bodies.
After you have read any 3 (to earn 1 hour of
category 1 CME credit) or all (to earn 3 hours of
credit) of these articles, please complete the CME Evaluation Form.
