Physicians in the United States, Canada, and Mexico
Physicians with current and valid licenses in the United
States, Canada, or Mexico who read any 3 of the selected continuing
medical education (CME) articles in this issue of Archives of
Neurology, complete the CME Evaluation Form, and fax it to the
number or mail it to the address at the bottom of the CME Evaluation
Form are eligible for category 1 CME credit. There is no charge.
The American Medical Association (AMA) is accredited by the
Accreditation Council for Continuing Medical Education to sponsor
continuing medical education for physicians. The AMA designates this
educational activity for up to 3 hours of category 1 CME credit per
Archives of Neurology issue toward the AMA Physician's
Recognition Award (PRA). Each physician should claim only
those hours of credit that were actually spent in this educational
activity.
Physicians in Other Countries
Physicians with current and valid licenses in the United States,
Mexico, or Canada are eligible for CME credit even if they live or
practice in other countries. Physicians licensed in other countries are
also welcome to participate in this CME activity. However, the PRA is
only available to physicians licensed in the United States, Canada, or
Mexico.
Statement of Educational Purpose
The Archives of Neurology provides new evidence for the
practice of neurology, neurosurgery, and other specialties whose goal
is to improve the neurological health of all people. Original
contributions, neurological reviews, neurology and public health, and
history of neurology are among the categories of articles published,
but all contributions receive a sympathetic reading by the Chief
Editor. The journal's editorial board sets the initial framework for
the types of articles published, which is then modified by feedback
from editors, external peer reviewers, authors, and readers. We are
keen to receive submissions from practicing neurologists to provide new
insight for colleagues.
We want our readers to assess each article critically; this CME
activity is active, not passive. Does the article contribute in some
way to the practice of neurology? How could you modify your practice
style to incorporate what you have learned? How can you acquire more
information, challenge the authors' conclusions, or verify what you
have read? Which of the articles in each issue is least helpful in your
quest for the best and most applicable evidence?
Earning Credit
To earn 1 hour of category 1 CME credit, you should read any
3 of the CME articles listed below and complete the CME
Evaluation Form. To
earn 3 hours of credit, read all of the articles listed below and complete the CME Evaluation Form.
The CME Evaluation Form must be submitted within 4 weeks of the issue date. A certificate
awarding up to 3 hours of category 1 CME credit will be faxed or mailed
to you; it is then your responsibility to maintain a record of credit
received. Questions about CME credit processing should be directed to
The Blackstone Group; tel: (312) 419-0400, ext 225; fax: (312)
269-1636.
CME Evaluation
One of our goals is to assess continually the needs of our readers so
we may enhance the educational effectiveness of the Archives of
Neurology. To achieve this goal, we need your help. You must
complete the CME Evaluation Form to receive credit.
CME Articles in This Issue of Archives of Neurology
The articles listed below may be read for CME
credit.
Sequence Analysis of
the Human Genome: Implications for the Understanding
of Nervous System Function and Disease (SEE ARTICLE)
Educational Objective:
To achieve an understanding of the impact that the human genome
sequence will have in defining neurological functions and causes of
disease.
Current Understanding of the Circadian Clock and the
Clinical Implications
for Neurological Disorders (SEE ARTICLE)
Educational Objective: To recognize the role of the
circadian clock
in neurological disorders.
Polymorphisms
in Inflammatory Genes and the Risk of Alzheimer Disease (SEE ARTICLE)
Educational Objective: To identify neurogenetic evidence
about inflammation as a risk factor in Alzheimer disease.
Feasibility of Gene Therapy for Late Neuronal Ceroid
Lipofuscinosis (SEE ARTICLE)
Educational Objective: To summarize
new therapies for late infantile neuronal ceroid lipofuscinosis.
Clinical and Pathological Diagnosis of Frontotemporal
Dementia: Report of the Work Group on Frontotemporal Dementia and
Pick's Disease (SEE ARTICLE)
Educational Objective: To
understand guidelines for the diagnosis of frontotemporal dementia.
The Genetic and Pathological Classification of Familial
Frontotemporal Dementia (SEE ARTICLE)
Educational Objective: To
explore the genetic and pathological basis
of frontotemporal dementia.
-Synuclein in Familial Alzheimer Disease:
Epitope Mapping Parallels Dementia With Lewy Bodies and Parkinson
Disease (SEE ARTICLE)
Educational Objective: To investigate the
-synuclein epitope mapping properties
of Lewy bodies in familial
Alzheimer disease.
Improvement in the Molecular Diagnosis of
Machado-Joseph Disease (SEE ARTICLE)
Educational Objective: To
recognize advances in the diagnosis
of Machado-Joseph disease.
Impact of DNA Testing for Early-Onset Familial Alzheimer
Disease and Frontotemporal Dementia (SEE ARTICLE)
Educational
Objective: To understand the personal and social impact
of DNA
testing in neurologic disorders.
The SCA12 Mutation
as a Rare Cause of Spinocerebellar Ataxia (SEE ARTICLE)
Educational
Objective: To investigate the relative frequency of SCA12
among familial and sporadic spinocerebellar ataxias.
Clinical
and Molecular Correlations in Spinocerebellar Ataxia Type 6:
A
Study of 24 Dutch Families (SEE ARTICLE)
Educational Objective:
To examine SCA6 mutations in spinocerebellar
ataxias in
the Netherlands.
Familial Progressive Supranuclear Palsy:
Detection of Subclinical Cases
Using 18F-Dopa and
18Fluorodeoxyglucose Positron Emission Tomography (SEE ARTICLE)
Educational Objective: To study regional dopaminergic and
glucose metabolism
in familial progressive supranuclear palsy.
Genetic and Clinical Analysis of Spinocerebellar Ataxia
Type 8 Repeat Expansion in Italy (SEE ARTICLE)
Educational
Objective: To determine the prevalence of SCA8 repeat
expansion in spinocerebellar ataxias.
Dorsal Forebrain Anomaly in Williams Syndrome (SEE ARTICLE)
Educational Objective: To examine forebrain anomalies in Williams syndrome.
TAU as a Susceptibility Gene for Amyotropic Lateral
SclerosisParkinsonism Dementia Complex of Guam (SEE ARTICLE)
Educational Objective: To study TAU protein in
amyotrophic lateral sclerosisparkinsonism dementia complex among Chamorro people of Guam.
Identification of a High Frequency
of Mutation at Exon 8 of the ATP7B Gene
in a Chinese Population With Wilson Disease by Fluorescent PCR (SEE ARTICLE)
Educational Objective: To learn more about the
neurogenetics of Chinese patients with Wilson disease.
Hearing Impairment Is Common in Various Phenotypes of the
Mitochondrial DNA A3243G Mutation (SEE ARTICLE)
Educational Objective: To study the clinical correlation of the
mitochondrial DNA A3243G mutation.
After you have read any 3 (to earn 1 hour of category 1 CME
credit) or all (to earn 3 hours
of credit) of these articles, please complete the CME Evaluation Form.