Physicians in the United States, Canada, and Mexico
Physicians with current and valid licenses in the United States, Canada, or Mexico who read any 3 of the selected continuing medical education (CME) articles in this issue of Archives of Neurology, complete the CME Evaluation Form, and fax it to the number or mail it to the address at the bottom of the CME Evaluation Form are eligible for category 1 CME credit. There is no charge.
The American Medical Association (AMA) is accredited by the Accreditation Council for Continuing Medical Education to sponsor continuing medical education for physicians. The AMA designates this educational activity for up to 3 hours of category 1 CME credit per Archives of Neurology issue toward the AMA Physician's Recognition Award (PRA). Each physician should claim only those hours of credit that were actually spent in this educational activity.
Physicians in Other Countries
Physicians with current and valid licenses in the United States, Mexico, or Canada are eligible for CME credit even if they live or practice in other countries. Physicians licensed in other countries are also welcome to participate in this CME activity. However, the PRA is only available to physicians licensed in the United States, Canada, or Mexico.
Statement of Educational Purpose
The Archives of Neurology provides new evidence for the practice of neurology, neurosurgery, and other specialties whose goal is to improve the neurological health of all people. Original contributions, neurological reviews, neurology and public health, and history of neurology are among the categories of articles published, but all contributions receive a sympathetic reading by the Chief Editor. The journal's editorial board sets the initial framework for the types of articles published, which is then modified by feedback from editors, external peer reviewers, authors, and readers. We are keen to receive submissions from practicing neurologists to provide new insight for colleagues.
We want our readers to assess each article critically; this CME activity is active, not passive. Does the article contribute in some way to the practice of neurology? How could you modify your practice style to incorporate what you have learned? How can you acquire more information, challenge the authors' conclusions, or verify what you have read? Which of the articles in each issue is least helpful in your quest for the best and most applicable evidence?
Earning Credit
To earn 1 hour of category 1 CME credit, you should read any 3 of the CME articles listed below and complete the CME Evaluation Form. To earn 3 hours of credit, read all of the articles listed below and complete the CME Evaluation Form. The CME Evaluation Form must be submitted within 4 weeks of the issue date. A certificate awarding up to 3 hours of category 1 CME credit will be faxed or mailed to you; it is then your responsibility to maintain a record of credit received. Questions about CME credit processing should be directed to The Blackstone Group; tel: (312) 419-0400, ext 225; fax: (312) 269-1636.
CME Evaluation
One of our goals is to assess continually the needs of our readers so we may enhance the educational effectiveness of the Archives of Neurology. To achieve this goal, we need your help. You must complete the CME Evaluation Form to receive credit.
CME Articles in This Issue of Archives of Neurology
The articles listed below may be read for CME credit.
Autotoxicity and Alzheimer Disease (SEE ARTICLE)
Educational Objective: To learn more about the molecular biology and immunology of Alzheimer disease.
Mechanisms of Neurodegenerative Disorders: Part 1: Protein Aggregates (SEE ARTICLE)
Educational Objective: To understand that neurodegeneration is linked with the accumulation of insoluble protein aggregates.
Mechanisms of Neurodegenerative Disorders: Part 2: Control of Cell Death (SEE ARTICLE)
Educational Objective: To examine the process of cell death in neurodegeneration.
The Preclinical Phase of Alzheimer Disease: A 22-Year Prospective Study of the Framingham Cohort (SEE ARTICLE)
Educational Objective: To recognize the preclinical and earliest clinical changes in Alzheimer disease.
Cortical Inflammation in Alzheimer Disease but Not Dementia With Lewy Bodies (SEE ARTICLE)
Educational Objective: To compare the cortical inflammation of Alzheimer disease and dementia with Lewy bodies.
Apolipoprotein E Polymorphism and Alzheimer Disease: The Indo-US Cross-National Dementia Study (SEE ARTICLE)
Educational Objective: To compare the molecular neuroepidemiology of Alzheimer disease in India and the USA.
Effect of Anti-inflammatory Medications on Neuropathological Findings in Alzheimer Disease (SEE ARTICLE)
Educational Objective: To examine the influence of anti-inflammatory medications on the pathology of Alzheimer disease.
The Course of Cognitive Impairment in Preclinical Alzheimer Disease: Three- and 6-Year Follow-up of a Population-Based Sample (SEE ARTICLE)
Educational Objective: To understand the value of neuropsychological testing in preclinical Alzheimer disease.
Region-Specific Neurotrophin Imbalances in Alzheimer Disease: Decreased Levels of Brain-Derived Neurotrophic Factor and Increased Levels of Nerve Growth Factor in Hippocampus and Cortical Areas (SEE ARTICLE)
Educational Objective: To learn whether neurotrophin proteins are altered in Alzheimer disease.
Progression of Parkinsonism and Loss of Cognitive Function in Alzheimer Disease (SEE ARTICLE)
Educational Objective: To assess the association of parkinsonism and cognitive decline in Alzheimer disease.
Left Frontotemporal Hypoperfusion Is Associated With Aggression in Patients With Dementia (SEE ARTICLE)
Educational Objective: To understand the association of aggression and left frontotemporal hypoperfusion in dementias.
Association Between Severe Cerebral Amyloid Angiopathy and Cerebrovascular Lesions in Alzheimer Disease Is Not a Spurious One Attributable to Apolipoprotein E4 (SEE ARTICLE)
Educational Objective: To learn about the neurogenetics of cerebral amyloid angiopathy and stroke in Alzheimer patients.
Assessing Financial Capacity in Patients With Alzheimer Disease: A Conceptual Model and Prototype Instrument (SEE ARTICLE)
Educational Objective: To learn about the Financial Capacity Instrument to evaluate tasks of financial ability in patients with Alzheimer disease.
Early-Onset Alzheimer Disease Caused by a New Mutation (V717L) in the Amyloid Precursor Protein Gene (SEE ARTICLE)
Educational Objective: To examine the molecular biology of dementia in a family with very early onset.
After you have read any 3 (to earn 1 hour of category 1 CME credit) or all (to earn 3 hours of credit) of these articles, please complete the CME Evaluation Form.
