Physicians in the United States, Canada, and Mexico
Physicians with current and valid licenses in the United States, Canada, or Mexico who read any 3 of the selected continuing medical education (CME) articles in this issue of Archives of Neurology, complete the CME Evaluation Form, and fax it to the number or mail it to the address at the bottom of the CME Evaluation Form are eligible for category 1 CME credit. There is no charge.
The American Medical Association (AMA) is accredited by the Accreditation Council for Continuing Medical Education to sponsor continuing medical education for physicians. The AMA designates this educational activity for up to 3 hours of category 1 CME credit per Archives of Neurology issue toward the AMA Physician's Recognition Award (PRA). Each physician should claim only those hours of credit that were actually spent in this educational activity.
Physicians in Other Countries
Physicians with current and valid licenses in the United States, Mexico, or Canada are eligible for CME credit even if they live or practice in other countries. Physicians licensed in other countries are also welcome to participate in this CME activity. However, the PRA is only available to physicians licensed in the United States, Canada, or Mexico.
Statement of Educational Purpose
The Archives of Neurology provides new evidence for the practice of neurology, neurosurgery, and other specialties whose goal is to improve the neurological health of all people. Original contributions, neurological reviews, neurology and public health, and history of neurology are among the categories of articles published, but all contributions receive a sympathetic reading by the Chief Editor. The journal's editorial board sets the initial framework for the types of articles published, which is then modified by feedback from editors, external peer reviewers, authors, and readers. We are keen to receive submissions from practicing neurologists to provide new insight for colleagues.
We want our readers to assess each article critically; this CME activity is active, not passive. Does the article contribute in some way to the practice of neurology? How could you modify your practice style to incorporate what you have learned? How can you acquire more information, challenge the authors' conclusions, or verify what you have read? Which of the articles in each issue is least helpful in your quest for the best and most applicable evidence?
Earning Credit and CME Evaluation Form
To earn 1 hour of category 1 CME credit, you should read any 3 of the CME articles listed below and complete the CME Evaluation Form. To earn 3 hours of credit, read all of the articles listed below and complete the CME Evaluation Form. The CME Evaluation Form must be submitted within 4 weeks of the issue date. A certificate awarding up to 3 hours of category 1 CME credit will be faxed or mailed to you; it is then your responsibility to maintain a record of credit received.
CME Articles in This Issue of Archives of Neurology
The articles listed below may be read for CME credit.
Mechanisms of High-Dose Intravenous Immunoglobulins in Demyelinating Diseases (SEE ARTICLE)
Educational Objective: To understand how high-dose intravenous immunoglobulins are an effective treatment for demyelinating diseases.
Genetic Linkage Analysis (SEE ARTICLE)
Educational Objective: To learn about the use of genetic linkage analysis to identify the biochemical basis of neurologic disorders.
Cerebrospinal Fluid 
-Amyloid(1-42) in Alzheimer Disease: Differences Between Early- and Late-Onset Alzheimer Disease and Stability During the Course of Disease (SEE ARTICLE)
Educational Objective: To examine the diagnostic value of cerebrospinal fluid -amyloid(1-42).
Domestic Violence Against Patients With Chronic Neurologic Disorders (SEE ARTICLE)
Educational Objective: To realize that patients with chronic neurologic disorders may suffer domestic violence.
Urinary Myelin Basic Protein–like Material in Patients With Multiple Sclerosis During Interferon Beta-1b Treatment (SEE ARTICLE)
Educational Objective: To determine the value of urine myelin basic protein–like material to manage therapy of patients with multiple sclerosis.
A Novel Mutation in the Gene for the Adult Skeletal Muscle Sodium Channel 
-Subunit (SCN4A) That Causes Paramyotonia Congenita of von Eulenburg (SEE ARTICLE)
Educational Objective: To read about the molecular biology of a Japanese family with paramyotonia congenita of von Eulenberg.
Microalbuminuria in Ischemic Stroke (SEE ARTICLE)
Educational Objective: To study microalbuminuria in patients with stroke.
Salvage Chemotherapy With Tamoxifen for Recurrent Anaplastic Astrocytomas (SEE ARTICLE)
Educational Objective: To study the effects of tamoxifen in young adult patients with recurrent anaplastic astrocytomas.
Deletions Causing Spinal Muscular Atrophy Do Not Predispose to Amyotrophic Lateral Sclerosis (SEE ARTICLE)
Educational Objective: To learn more about the neurogenetics of amyotrophic lateral sclerosis.
Familial Paroxysmal Dystonic Choreoathetosis: Clinical Findings in a Large Japanese Family and Genetic Linkage to 2q (SEE ARTICLE)
Educational Objective: To study the clinical findings and neurogenetics of paroxysmal dystonic choreoathetosis in a Japanese family.
Trigeminal Neuralgia Triggered by Auditory Stimuli in Multiple Sclerosis (SEE ARTICLE)
Educational Objective: To recognize trigeminal neuralgia triggered by auditory stimuli in multiple sclerosis.
Stroke: How Large a Public Health Problem, and How Can the Neurologist Help? (SEE ARTICLE)
Educational Objective: To recognize that stroke is an important public health problem globally.
