Physicians in the United States, Canada, and Mexico
Physicians with current and valid licenses in the United States, Canada, or Mexico who read any 3 of the selected continuing medical education (CME) articles in this issue of Archives of Neurology, complete the CME Evaluation Form, and fax it to the number or mail it to the address at the bottom of the CME Evaluation Form are eligible for category 1 CME credit. There is no charge.
The American Medical Association (AMA) is accredited by the Accreditation Council for Continuing Medical Education to sponsor continuing medical education for physicians. The AMA designates this educational activity for up to 3 hours of category 1 CME credit per Archives of Neurology issue toward the AMA Physician's Recognition Award (PRA). Each physician should claim only those hours of credit that were actually spent in this educational activity.
Physicians in Other Countries
Physicians with current and valid licenses in the United States, Mexico, or Canada are eligible for CME credit even if they live or practice in other countries. Physicians licensed in other countries are also welcome to participate in this CME activity. However, the PRA is only available to physicians licensed in the United States, Canada, or Mexico.
Statement of Educational Purpose
The Archives of Neurology provides new evidence for the practice of neurology, neurosurgery, and other specialties whose goal is to improve the neurological health of all people. Original contributions, neurological reviews, neurology and public health, and history of neurology are among the categories of articles published, but all contributions receive a sympathetic reading by the Chief Editor. The journal's editorial board sets the initial framework for the types of articles published, which is then modified by feedback from editors, external peer reviewers, authors, and readers. We are keen to receive submissions from practicing neurologists to provide new insight for colleagues.
We want our readers to assess each article critically; this CME activity is active, not passive. Does the article contribute in some way to the practice of neurology? How could you modify your practice style to incorporate what you have learned? How can you acquire more information, challenge the authors' conclusions, or verify what you have read? Which of the articles in each issue is least helpful in your quest for the best and most applicable evidence?
Earning Credit and CME Evaluation Form
To earn 1 hour of category 1 CME credit, you should read any 3 of the CME articles listed on the next page and complete the CME Evaluation Form on page 131. To earn 3 hours of credit, read all of the articles listed on the next page and complete the CME Evaluation Form. The CME Evaluation Form must be submitted within 4 weeks of the issue date. A certificate awarding up to 3 hours of category 1 CME credit will be faxed or mailed to you; it is then your responsibility to maintain a record of credit received.
CME Articles in This Issue of Archives of Neurology
The following articles may be read for CME credit.
Late-Onset Myasthenia Gravis: A Changing Scene (SEE ARTICLE)
Educational Objective: To understand that late onset myasthenia gravis has differentiating characteristics
Stem Cell Technology for Basic Science and Clinical Applications (SEE ARTICLE)
Educational Objective: To learn about the clinical relevance of stem cell technology to repopulate regions of the adult central nervous system
Diagnostic Criteria for Parkinson Disease (SEE ARTICLE)
Educational Objective: To learn about the clinical and neuropathological criteria for the diagnosis of definite, probable, and possible Parkinson disease
Spinocerebellar Ataxia Type 2: Clinical Features of a Pedigree Displaying Prominent Frontal-Executive Dysfunction (SEE ARTICLE)
Educational Objective: To learn about the clinical features of spinocerebellar ataxia type 2 in an Australian pedigree
The Heidenhain Variant of Creutzfeldt-Jakob Disease (SEE ARTICLE)
Educational Objective: To study the radiologic and pathologic findings in patients with the Heidenhain variant of Creutzfeldt-Jakob disease
A Pedigree With a Novel Presenilin 1 Mutation at a Residue That Is Not Conserved in Presenilin 2 (SEE ARTICLE)
Educational Objective: To learn about a presenilin 1 gene responsible for early-onset Alzheimer disease
Decreases in T-Cell Tumor Necrosis Factor 
Binding With Interferon Beta Treatment in Patients With Multiple Sclerosis (SEE ARTICLE)
Educational Objective: To learn whether interferon beta treatment affects T-cell tumor necrosis factor binding in patients with MS
T-Cell Apoptosis in Inflammatory Neuromuscular Disorders Associated With Human Immunodeficiency Virus Infection (SEE ARTICLE)
Educational Objective: To examine regulation of T-cell elimination in patients with human immunodeficiency syndrome with inflammatory neuromuscular disorders
Peripheral Nerve Function in HIV Infection: Clinical, Electrophysiologic, and Laboratory Findings (SEE ARTICLE)
Educational Objective: To learn about the effects of nutrition, systemic disease, and immune deficiency on peripheral nerve function in people with acquired immunodeficiency syndrome
Multiple-System Atrophy: The Putative Causative Role of Environmental Toxins (SEE ARTICLE)
Educational Objective: To examine the role of environmental toxins in patients with multiple system atrophy
Clinical Correlates of Vascular Parkinsonism (SEE ARTICLE)
Educational Objective: To learn about the clinical features of vascular parkinsonism as a distinct clinical entity
Developmental Deficits in Adult Patients With Arteriovenous Malformations (SEE ARTICLE)
Educational Objective: To understand that developmental learning disorders are sensitive markers of early cerebral status in patients with arteriovenous malformations
Marchiafava-Bignami Disease: Computed Tomographic Scan, 99Tc HMPAO-SPECT, and FLAIR MRI Findings in a Patient With Subcortical Aphasia, Alexia, Bilateral Agraphia, and Left-handed Deficit of Constructional Ability (SEE ARTICLE)
Educational Objective: To learn about the neuropsychological and neuroimaging findings of a patient with probable Marchiafava-Bignami disease
Isolated, Chronic, Epilepsia Partialis Continua in an HIV-Infected Patient (SEE ARTICLE)
Educational Objective: To recognize that isolated, chronic epilepsia partialis continua may be a manifestation of human immunodeficiency virus infection
