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Enough Is EnoughMoving on to Deep Brain Stimulation in Patients With Fluctuating Parkinson Disease
Michael S. Okun, MD;
Kelly D. Foote, MD
Arch Neurol. 2009;66(6):778-780.
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JAMA
Bilateral Deep Brain Stimulation vs Best Medical Therapy for Patients With Advanced Parkinson Disease: A Randomized Controlled Trial
Frances M. Weaver, PhD; Kenneth Follett, MD, PhD; Matthew Stern, MD; Kwan Hur, PhD; Crystal Harris, PharmD; William J. Marks Jr, MD; Johannes Rothlind, PhD; Oren Sagher, MD; Domenic Reda, PhD; Claudia S. Moy, PhD; Rajesh Pahwa, MD; Kim Burchiel, MD; Penelope Hogarth, MD; Eugene C. Lai, MD, PhD; John E. Duda, MD; Kathryn Holloway, MD; Ali Samii, MD; Stacy Horn, DO; Jeff Bronstein, MD, PhD; Gatana Stoner, RN, CCRC; Jill Heemskerk, PhD; Grant D. Huang, PhD; for the CSP 468 Study Group
Context: Deep brain stimulation is an accepted treatment for advanced Parkinson disease (PD), although there are few randomized trials comparing treatments, and most studies exclude older patients.
Objective: To compare 6-month outcomes for patients with PD who received deep brain . . . [Full Text of this Article] INTERDISCIPLINARY AND MULTIDISCIPLINARY SCREENING
IMPORTANCE AND DIFFICULTY OF INCLUDING A MEDICAL THERAPY GROUP IN DBS STUDIES
OLDER AGE AND DBS
MOTOR IMPROVEMENTS
QUALITY OF LIFE IMPROVES WITH DBS
COGNITIVE WORSENING WITH DBS
ADVERSE EVENT REPORTING NEEDS TO IMPROVE IN DBS STUDIES
CONCLUSIONS
AUTHOR INFORMATION
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Bilateral Deep Brain Stimulation vs Best Medical Therapy for Patients With Advanced Parkinson Disease: A Randomized Controlled Trial
Frances M. Weaver, Kenneth Follett, Matthew Stern, Kwan Hur, Crystal Harris, William J. Marks, Jr, Johannes Rothlind, Oren Sagher, Domenic Reda, Claudia S. Moy, Rajesh Pahwa, Kim Burchiel, Penelope Hogarth, Eugene C. Lai, John E. Duda, Kathryn Holloway, Ali Samii, Stacy Horn, Jeff Bronstein, Gatana Stoner, Jill Heemskerk, Grant D. Huang, and for the CSP 468 Study Group
JAMA. 2009;301(1):63-73.
ABSTRACT
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