 |
|
Deep Brain Stimulation, Neuroethics, and the Minimally Conscious StateMoving Beyond Proof of Principle
Nicholas D. Schiff, MD;
Joseph T. Giacino, PhD;
Joseph J. Fins, MD
Arch Neurol. 2009;66(6):697-702.
|
|
| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
|
|
|
INTRODUCTION
We briefly review the motivation, ethical framing, and results of a recent single-subject study of central thalamic deep brain stimulation (DBS) in a patient remaining in the chronic minimally conscious state (MCS). In the study, a severely brain-injured human subject showed behavioral improvements in attentive responsiveness, limb control, recovery of oral feeding, and spoken language following central thalamic DBS.1 These findings are placed into the context of, and contrasted with, prior efforts applying thalamic brain stimulation to patients in the vegetative state (VS). Efforts to develop DBS for recovery of function in the setting of disorders of consciousness must meet several challenges presented by the expected wide variance of underlying brain injuries and need to carefully identify potential goals of therapeutic intervention. Although the study involved only a single subject, the results demonstrate a causal relationship between brain . . . [Full Text of this Article]
RATIONALE
SINGLE-SUBJECT STUDY OF DBS IN MCS
COMPARISON WITH EARLIER STUDIES
SCIENTIFIC OPPORTUNITIES
CHALLENGES AND LIMITATIONS
ETHICAL IMPLICATIONS
AUTHOR INFORMATION
Author Affiliations: Department of Neurology and Neuroscience (Dr Schiff) and Division of Medical Ethics (Dr Fins), Weill Medical College of Cornell University, New York, New York; and JFK Johnson Rehabilitation Institute and New Jersey Neuroscience Institute, JFK Medical Center, Edison (Dr Giacino).
 CiteULike  Connotea  Del.icio.us  Digg  Reddit  Technorati  Twitter
What's this?
RELATED ARTICLE
This Month in Archives of Neurology
Arch Neurol. 2009;66(6):689-690.
FULL TEXT
|
