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by Lewis P. Rowland, MD, 176 pp, $24.95, ISBN 13: 978-0-19-537952-5, New York, New York, Oxford University Press, 2008.

Roger N. Rosenberg, MD, Reviewer

Arch Neurol. 2009;66(3):415.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Notable partnerships in medicine and science have included Hubel and Wiesel, Watson and Crick, Jacob and Monod, Jasper and Penfield, and Kety and Schmidt, among others. Their joint efforts were synergistic and mutually beneficial. Their combined careers allowed both to prosper and brought esteem by colleagues that was equally shared. Rowland describes vividly the partnership of Putnam and Merritt in their research in 1938 to develop the anticonvulsant diphenylhydantoin (now phenytoin) with the trade name Dilantin (Pfizer, New York, New York). The scientific achievement of Putnam and Merritt is monumental, as diphenylhydantoin has proved to be a major contribution to combat epilepsy. Their personal outcomes, however, were in stark contrast compared with other scientific partnerships and the reasons and facts for this disparity, as provided by Rowland in graphic style, is a story of Shakespearean proportion. The real story conveyed by Rowland is the personal . . . [Full Text of this Article]

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