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Roger N. Rosenberg, MD, Editor

Arch Neurol. 2009;66(3):311-312.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

JAMA

Effect of Physical Activity on Cognitive Function in Older Adults at Risk for Alzheimer Disease: A Randomized Trial

Nicola T. Lautenschlager, MD; Kay L. Cox, PhD; Leon Flicker, MBBS, PhD; Jonathan K. Foster, DPhil; Frank M. van Bockxmeer, PhD; Jianguo Xiao, MD, PhD; Kathryn R. Greenop, PhD; Osvaldo P. Almeida, MD, PhD

Context:  Many observational studies have shown that physical activity reduces the risk of cognitive decline; however, evidence from randomized trials is lacking.

Objective:  To determine whether physical activity reduces the rate of cognitive decline among older adults at risk.

Design and Setting:  Randomized controlled trial of a 24-week physical activity intervention conducted between 2004 and 2007 in metropolitan Perth, Western Australia. Assessors of cognitive function were blinded to group membership.

Participants:  We recruited volunteers who reported memory problems but did not meet criteria for dementia. Three hundred eleven individuals aged 50 years . . . [Full Text of this Article]

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