This Article  • Full text  • PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Contact me when this article is cited  Related Content  • Related article  • Related letter  • Similar articles in this journal  Topic Collections  • Cerebrovascular Disease  • Stroke  • Nutritional and Metabolic Disorders  • Nutrition/ Malnutrition  • Evidence-Based Medicine  • Diet  • Alert me on articles by topic  Social Bookmarking   What's this?

Kara Lea Kliewer, RD, LDN

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

As a registered dietitian working in a neurology intensive care unit, I took interest in the results of the study by Yoo et al¹ published in the January 2008 issue of the Archives regarding the effect of undernutrition on clinical outcome in ischemic stroke patients. As an advocate of evidence-based nutrition and medicine, I am concerned by the lack of evidence-based criteria used to diagnose undernutrition in this study.

Low serum levels of albumin, prealbumin, and transferrin were 3 of the 5 parameters selected to assess nutritional status in the Yoo et al¹ study. Decades of published evidence, however, indicate these hepatic proteins are neither sensitive nor specific to nutritional status.² After an injury (including brain tissue damage in ischemic stroke), a patient's inflammatory response to stress results in an increased production of cytokines that act to suppress production of the "negative" acute-phase hepatic proteins . . . [Full Text of this Article]

AUTHOR INFORMATION



CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

RELATED ARTICLE

Undernutrition as a Predictor of Poor Clinical Outcomes in Acute Ischemic Stroke Patients
Sung-Hee Yoo, Jong S. Kim, Sun U. Kwon, Sung-Cheol Yun, Jae-Young Koh, and Dong-Wha Kang
Arch Neurol. 2008;65(1):39-43.
ABSTRACT | FULL TEXT  

RELATED LETTER

Nutrition and Ischemic Stroke—Reply
Sung-Hee Yoo and Dong-Wha Kang
Arch Neurol. 2008;65(9):1257-1258.
EXTRACT | FULL TEXT