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edited by Turgut Tatlisumak, MD, PhD, and Marc Fisher, MD, 579 pp, with illus, $200, ISBN 0-521-83814-2, New York, NY, Cambridge University Press, 2006.

Matthew S. Goldberg, PhD, Reviewer

Arch Neurol. 2008;65(9):1255-1256.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

The expanding literature on animal models of neurological diseases reflects advances in methods to generate animal models, particularly transgenic mice; advances in methods for analysis; and advances in our understanding of the molecular mechanisms of neurological diseases that allow pathophysiological hypotheses and potential treatments to be tested in animal models. The lack of a single source for the practical information required to use animal models of neurological diseases can be frustrating. This highlights the need for a comprehensive yet concise and practical handbook. This book uniquely meets this need and provides a useful guide for clinicians and researchers interested in an overview of existing experimental models of major neurological diseases as well as a practical guide for researchers seeking to implement the latest methods and techniques.

Each chapter is written by experts on an individual topic. Part 1 (the first 17 chapters) is divided roughly . . . [Full Text of this Article]

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