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  Vol. 65 No. 7, July 2008 TABLE OF CONTENTS
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COMMENTS AND OPINIONS
Antihypertensive Medications Influence the Rate of Conversion From Mild Cognitive Impairment to Alzheimer Disease

Luca Rozzini, MD; Barbara Vicini Chilovi, MD; Marco Trabucchi, MD, PhD; Alessandro Padovani, MD, PhD

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

We read with interest the article by Reitz et al1 showing that a history of hypertension is related to a higher risk of mild cognitive impairment (MCI). To further discuss this topic, we analyzed 80 subjects consecutively recruited in our clinic who met the operational criteria for MCI at 2 years' follow-up. Subjects with conversion to Alzheimer disease over time were classified as having dementia; subjects who remained unchanged during follow-up were defined as stable. Sociodemographic and clinical characteristics are shown in the Table. When analyzed in a logistic regression model, older age (> 72 years) and Alzheimer Disease Assessment Scale, Cognitive Subscale basal score (> 9.5 points) were independently associated with the conversion to Alzheimer disease (older age: odds ratio, 9.9; 95% confidence interval, 2.2-43.9; P = .003; and Alzheimer Disease Assessment Scale, Cognitive Subscale basal . . . [Full Text of this Article]

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