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COMMENTS AND OPINIONS
Differential Diagnosis Between Acute Disseminated Encephalomyelitis and Multiple Sclerosis During the First Episode
Eleonora Tavazzi, MD;
Sabrina Ravaglia, MD, PhD;
Diego Franciotta, MD;
Enrico Marchioni, MD
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We have read with interest the recent article by de Seze et al1 titled "Acute Fulminant Demyelinating Disease: A Descriptive Study of 60 Patients." The article mainly tackles the problem of different diagnosis criteria between acute disseminated encephalomyelitis (ADEM) and multiple sclerosis (MS) during the acute phase of the first episode in a population aged 15 years and older. From this study, it has emerged that the following variables help to distinguish patients with ADEM from patients with MS: atypical symptoms, oligoclonal bands, and gray matter involvement. When referring to adults, de Seze and colleagues cite only the work by Schwarz et al,2 underlining some differential characteristics having to do with age and the distribution of lesions on magnetic resonance imaging. The same topic appears among our subjects of interest, as can be seen from our articles . . . [Full Text of this Article]AUTHOR INFORMATION
RELATED ARTICLE
Acute Fulminant Demyelinating Disease: A Descriptive Study of 60 Patients
Jérôme de Seze, Marc Debouverie, Hélène Zephir, Christine Lebrun, Frédéric Blanc, Véronique Bourg, Sandrine Wiertlewski, Sophie Pittion, David Laplaud, Emmanuelle Le Page, Romain Deschamps, Philippe Cabre, Jean Pelletier, Irina Malikova, Pierre Clavelou, Valérie Jaillon, Gilles Defer, Pierre Labauge, Olivier Gout, Clotilde Boulay, Gilles Edan, and Patrick Vermersch
Arch Neurol. 2007;64(10):1426-1432.
ABSTRACT
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RELATED LETTER
Differential Diagnosis Between Acute Disseminated Encephalomyelitis and Multiple Sclerosis During the First Episode—Reply
Jérôme de Seze
Arch Neurol. 2008;65(5):677.
EXTRACT
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