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COMMENTS AND OPINIONS
Monophasic Acute, Recurrent, and Multiphasic Disseminated Encephalomyelitis and Multiple Sclerosis—Reply
Jérôme de Seze, MD, PhD
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In reply
My coauthors and I thank Drs Brinar and Habek for their interesting comments. We agree that MDEM, RDEM, DEM, and ADEM may be confusing. However, as stated in our study, we did not have RDEM but only monophasic ADEM, recurrent ADEM (with the same symptoms), and MS. The difference between multiphasic ADEM and MS may be difficult to distinguish, but we did not identify patients with recurrent ADEM.
Second, none of our patients had clinical signs of polyneuropathy, but we did not systematically perform electromyography in them.
Third, 2 of our 19 patients with MS (10.5%) had extended myelitis, a rare feature in MS. However, although it is rare in MS, extended myelitis represents about 10% of MS cases.1-2
Biopsies were only performed for patients with a final diagnosis of ADEM, but we have no other details concerning these biopsies.
Finally, we agree . . . [Full Text of this Article] AUTHOR INFORMATION
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ABSTRACT
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RELATED LETTER
Monophasic Acute, Recurrent, and Multiphasic Disseminated Encephalomyelitis and Multiple Sclerosis
Vesna V. Brinar and Mario Habek
Arch Neurol. 2008;65(5):675-676.
EXTRACT
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