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Nancy Minshew, MD; Diane L. Williams, PhD

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In reply

Skoyles argues in his letter to the editor against the case for advances in the understanding of the neurobiology of autism articulated in our review.¹ Our article summarized the impressive changes in the conceptualization of autism resulting from the past 15 to 20 years of research. The article did not propose that a final answer had been arrived at or even that all the new discoveries had been covered, given the 3000-word limit. We provide further elaboration in a review article that is in press² and add related advances in genetics and developmental neurobiology in a forthcoming book chapter.³

Skoyles criticizes the studies cited for being based on group differences, noting that the overlap in results between autism and nonautism cases means that the trait studied is also present in some members of the control group. It would be hard to . . . [Full Text of this Article]

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RELATED LETTER

No New Neurobiology Yet for Autism
John Robert Skoyles
Arch Neurol. 2008;65(1):155.
EXTRACT | FULL TEXT  

RELATED ARTICLE

The New Neurobiology of Autism: Cortex, Connectivity, and Neuronal Organization
Nancy J. Minshew and Diane L. Williams
Arch Neurol. 2007;64(7):945-950.
ABSTRACT | FULL TEXT