This Article  • Full text  • PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Topic Collections  • Immunologic Disorders  • Movement Disorders  • Multiple Sclerosis/ Demyelinating Disease  • Tremor  • Alert me on articles by topic

Edward R. Hammond, MD, MPH; Douglas A. Kerr, MD, PhD

Arch Neurol. 2008;65(1):142-143.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

A 29-year old white man presented with gait imbalance and visual disturbances 6 years ago. Evaluation of his condition led to a diagnosis of multiple sclerosis (MS). He experienced disease progression while taking 2 different conventional MS treatments that manifested as new-onset tremor in both hands, progressing to involve the hands and neck. He occasionally drinks alcohol and has no family history of tremor. Over the next 4 years, he averaged 3 relapses per year and 6 enhancing lesions per year on magnetic resonance imaging scans with gadolinium contrast (Omniscan), including 1 cerebellar lesion. Twenty-two months earlier he had been treated with high-dose intravenous cyclophosphamide (Revimmune), 200 mg/kg, over 4 days under a research study protocol at Johns Hopkins Hospital. He has not been receiving any immunomodulatory treatment since the Revimmune protocol. Over this period he has had no exacerbations . . . [Full Text of this Article]

COMMENT


AUTHOR INFORMATION