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COMMENTS AND OPINIONS
Spinchter Symptoms as Predictors of Long-term Disability in Multiple Sclerosis
Margaret L. Frazer, MD;
J. Thomas Benson, MD;
Clare A. Braun Hashemi, MD;
Heidi Lee, MD;
Karen D. Rodman, MD;
Oldrich J. Kolar, MD, PhD
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In the recently published communication by Langer-Gould et al1 addressing predictors of long-term disability in patients with relapsing-remitting multiple sclerosis (MS), sphincter symptoms and a short interval between the first and second attack were indicated as the most reliable predictors of long-term disability. It was recommended that these factors should be considered before treatment using the currently accepted disease-modifying agents is considered. However, without further specification of the sphincter symptoms, particularly with no objective findings indicating sphincter dysfunction, the actual clinical implication of the recommendation in individual MS patients could prove to have a negative effect on timely treatment.
Subjective symptoms of urgency, frequency, feeling of incomplete evacuation of urinary bladder, episodic incontinence, or transient inability to initiate urination are very frequent complaints in MS . . . [Full Text of this Article] AUTHOR INFORMATION
RELATED LETTER
Spinchter Symptoms as Predictors of Long-term Disability in Multiple Sclerosis—Reply
Annette Langer-Gould
Arch Neurol. 2007;64(9):1359.
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RELATED ARTICLE
Clinical and Demographic Predictors of Long-term Disability in Patients With Relapsing-Remitting Multiple Sclerosis: A Systematic Review
Annette Langer-Gould, Rita A. Popat, Stella M. Huang, Kristin Cobb, Paulo Fontoura, Michael K. Gould, and Lorene M. Nelson
Arch Neurol. 2006;63(12):1686-1691.
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