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COMMENTS & OPINIONS
Other Important Aspects of Human T-Lymphotropic Virus 1–Associated Myelopathy—Reply
Stéphane Olindo, MD;
Agnès Lézin, PhD;
Didier Smadja, MD
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In reply
We thank Lima et al for their interesting comments and questions on our recent study.1 In our cohort, only 3 patients were coinfected with human immunodeficiency virus; subsequently, this parameter has not been analyzed.
Clinical features of HTLV-1–associated HAM/TSP combine paraparesis, sphincter disturbances, and sensory symptoms such as numbness in lower limbs and low back pain. In our study cohort, we used Kurtzke Disability Status Scale (DSS) score to assess patients. We chose strategic end points that were easy to define over the disease course, such as permanent unilateral or bilateral aid in walking, wheelchair confinement, or death related to the disease. Sphincter disturbances were not analyzed in this work. We agree with Lima et al that this symptom plays an important role in HAM/TSP disability. Assignment of a DSS score of 10 may also be directly influenced by . . . [Full Text of this Article] AUTHOR INFORMATION
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RELATED LETTER
Other Important Aspects of Human T-Lymphotropic Virus 1–Associated Myelopathy
Marco A. Lima, Ana C. Leite, Marcus T. Silva, and Abelardo Q. Araújo
Arch Neurol. 2007;64(7):1059.
EXTRACT
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RELATED ARTICLE
Natural History of Human T-Lymphotropic Virus 1–Associated Myelopathy: A 14-Year Follow-up Study
Stéphane Olindo, Philippe Cabre, Agnes Lézin, Harold Merle, Martine Saint-Vil, Aissatou Signate, Mickael Bonnan, Aurelie Chalon, Lionel Magnani, Raymond Cesaire, and Didier Smadja
Arch Neurol. 2006;63(11):1560-1566.
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