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Joana Guimarães, MD; Maria José Sá

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The study "Brain Abnormalities in Neuromyelitis Optica" by Pittock et al¹ attracted our attention because of its important description of the existence of brain involvement in neuromyelitis optica (NMO). Taking into account those observations and the ensuing revision of diagnosis criteria for NMO, we recently reported² the first Portuguese clinical case of NMO with positive results for serological NMO-IgG and abnormal brain magnetic resonance image (MRI) findings.

A 48-year-old woman was admitted at the department of neurology of Hospital de São João–Porto in 2003 because of sudden right crural paresis; the neurological examination showed a second degree monoparesis and bilateral hypoesthesia with a level by T7. She had a history of left optic neuritis 10 years previous. Cervical spinal MRI revealed cord widening with central hypointensity at T1 and hyperintensity at T2 and from C4 through L1. Cerebral MRI disclosed bihemispheric, confluent, subcortical, T2 . . . [Full Text of this Article]

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