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Treating Ocular Myasthenia Gravis With Inadequate Evidence
E. S. Roach, MD
Arch Neurol. 2007;64(12):1794-1795.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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The essence of wisdom is the ability to make the right decision on the basis of inadequate evidence.—Alan Gregg
We do not know the best way to treat ocular myasthenia gravis (OMG). Every day we must recommend therapy despite the limitations of our knowledge, and the promise of a yet-to-be-completed study is not very helpful for individuals who must decide about treatment now. Gilbert et al1 and Chavis and colleagues2 agree that many patients with OMG go on to develop generalized MG (GMG) and that preventing this progression is desirable. They also agree that immunotherapy with corticosteroids or thymectomy seems to work for OMG. There is concern, however, about the risks of long-term corticosteroid therapy or a major operation, such as thymectomy, and whether these risks can be justified in an individual with only ocular symptoms. The evidence that early immunotherapy in individuals with OMG . . . [Full Text of this Article] AUTHOR INFORMATION
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