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edited by Rajesh Pahwa, Kelly E. Lyons, 520 pp, with illus, $229.95, ISBN 0849376211, Informa Healthcare USA Inc, New York, New York, 2007.

Shilpa Chitnis, MD, PhD, Reviewer

Arch Neurol. 2007;64(11):1670.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

The new edition of this book is a comprehensive update on one of the most common and complex neurodegenerative diseases. The handbook comprises an extensive list of chapters, addressing all elements of Parkinson disease. Each chapter is sufficiently detailed with an extensive list of references for further reading. The chronology of chapters is well arranged from history to epidemiology, followed by pathophysiology, diverse clinical manifestations and comorbidities, neuroimaging techniques, animal models, genetics, and, last but not least, comprehensive medical and surgical management along with ancillary therapies for Parkinson disease.

The list of contributors is a "Who's Who" in movement disorders composed of authoritative experts, extensively published in their respective areas of expertise, which is reflected in the state-of-the-art reviews. The chapters on neuropathology, neurochemistry of nigral degeneration, neurophysiology, and neuron circuitry along with animal models offer insight into basic science aspects of Parkinson disease. A . . . [Full Text of this Article]

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