This Article  • Full text  • PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Topic Collections  • Oncology  • Brain Cancer  • Dermatology  • Melanoma  • Alert me on articles by topic

Cerebrospinal Fluid Findings

Arch Neurol. 2006;63:910.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

A 62-year-old man with microcellular lung cancer (T3N1M1, stage IV) diagnosed 5 months prior sought care for sudden right-sided limb weakness and speech disturbance. Neurologic examination revealed hemiparesis of the right limbs and motor dysphasia. In the next few days, he developed left external ophthalmoplegia with left peripheral facial palsy, left unilateral paralysis of the soft palate, and cognitive impairment, including lethargy and confusion. The findings from contrast-enhanced brain computed tomographic scans performed on 2 occasions were normal. Cerebrospinal fluid examination revealed 92 cells, 81 of which were poorly differentiated malignant cells (Figure 1 and Figure 2), a low glucose level of 2.10 mmol/L (37.8 mg/dL), protein level of 1.69 g/L, and elevated lactate dehydrogenase levels (301 U/L). Magnetic resonance imaging was not performed because the patient died as a result of complications (sepsis and pneumonia).

Figure appears in full text version. Figure 1. Metastatic malignant cells in cerebrospinal fluid. Several well-preserved malignant cells, . . . [Full Text of this Article]

AUTHOR INFORMATION

Mario Habek, MD; Damir Petravi, MD, PhD; Koraljka Gjadrov-Kuvedi, MD, MS; Daria Mahovi Lakui, MD