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Atypical Appearance of a Primary Central Nervous System Lymphoma
Arch Neurol. 2006;63:908-909.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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A 37-year-old female cachectic, immunocompetent, human immunodeficiency virusnegative patient (weight, 39 kg) presented with a slowly progressive paraparesis and a mild fluctuating psychotic pathology developing over half a year. Because of a limited spectrum of food intake that mainly consisted of falafel (containing Lathyrus sativus), neurolathyrism was suspected during a previous hospitalization. However, incommensurate with that diagnosis, a cerebral magnetic resonance imaging scan (Figure, A-C) showed an uncommon, remarkable, multifocal, streaklike contrast enhancement that appeared to follow the perivascular spaces. A spinal magnetic resonance imaging scan displayed a myelopathy with swelling of the whole spinal cord.
Figure appears in full text version.
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Figure. Cerebral magnetic resonance imaging demonstrating leukoencephalopathy in turbo inversion recovery magnitude sequences (A) and uncommon streaklike contrast enhancement in T1-weighted sequences (B and C). Immunohistochemistry revealed massive perivascular infiltration by small CD20-positive B cells (D [hematoxylin-eosin, original magnification x200] and E (CD20 staining, original magnification x200) with a . . . [Full Text of this Article]
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AUTHOR INFORMATION
George Trendelenburg, MD;
Claus Zimmer, MD;
Annette Forschler, MD;
Christine Stadelmann, MD;
Rolf Zschenderlein, MD
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