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Sudden Onset of Somnolence in Parkinson DiseaseReply
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We are grateful for the point Drs Morgan and Sethi raised, and we returned to our initial data collection forms to determine the cause of this problem. We discovered that although the participating neurologists depicted their patients' H&Y stages using some half-point increments (stage 0, 1, 1.5, 2, 2.5, 3, 4, 5) in programming the data for analysis, these scores were inadvertently coded ordinally with values of 1, 2, 3, 4, 5, 6, 7, and 8, respectively. This produced the effect noted by Drs Morgan and Sethi, an artificial expansion of the upper end of the scale's range.
We have now rerun all analyses with the correct H&Y scores. The study subjects' mean score is now 1.8 rather than 3.6; patients taking only levodopa still had higher-than-average PD severity, although that score is now 2.4 rather than 4.6. A revised version of Table 3 is appended, reflecting these . . . [Full Text of this Article] AUTHOR INFORMATION
Jerry Avorn, MD;
Sebastian Schneeweiss, MD, ScD;
Lewis R. Sudarsky, MD;
Robert J. Glynn, PhD, ScD
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Sudden Onset of Somnolence in Parkinson Disease
John C. Morgan and Kapil D. Sethi
Arch Neurol. 2006;63(3):467.
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