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Parkinson Disease With Severe Tremor but Otherwise Mild Deterioration
Arch Neurol. 2006;63:321-322.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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In this issue of the ARCHIVES, Josephs et al1 describe the features of a cohort of 16 patients with Parkinson disease (PD) who developed moderate to severe rest tremor, but otherwise suffered less disability than is typical during a decade of observation. Most patients had a family history of tremor, and pharmacologic responsiveness of tremor appeared to be disappointing. Based on their observations, the authors propose recognizing benign tremulous parkinsonism as a subtype of PD, a term that has been previously suggested.2 Is this a valid categorization, and is it useful for understanding the etiology of PD or managing its symptoms?
THE RATIONALE FOR CLASSIFYING AND SUBCLASSIFYING PARKINSONISM
According to the Chinese, getting the grouping and naming right is the first step to wisdom. The syndrome of idiopathic degenerative parkinsonism has as subdivisions PD, progressive supranuclear palsy, multiple system atrophy, and corticobasal degeneration.3 In the past few decades these have become accepted as distinct clinicopathological . . . [Full Text of this Article] REST TREMOR AND THE DISEASES THAT PRODUCE IT
ASSOCIATION OF REST TREMOR WITH PROGNOSIS IN PD
BENIGN TREMULOUS PARKINSONISM?
AUTHOR INFORMATION
Padraig E. OSuilleabhain, MD
RELATED ARTICLE
Benign Tremulous Parkinsonism
Keith A. Josephs, Joseph Y. Matsumoto, and J. Eric Ahlskog
Arch Neurol. 2006;63(3):354-357.
ABSTRACT
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