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  Vol. 63 No. 12, December 2006 TABLE OF CONTENTS
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RESEARCH LETTER
Neutralizing Antibodies Against Botulinum Toxin A After a Wasp Sting

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

There are many reports on the neurological sequelae of wasp stings, including antibody development leading to autoimmune neuromyotonia.1 We report a complete therapy failure of botulinum neurotoxin A due to antibody formation after a wasp sting and discuss its implications.

Report of a Case

In a 47-year-old woman with idiopathic cervical dystonia (Tsui score, 6; Toronto Western Spasmodic Torticollis Rating Scale [TWSTRS] score, 10), treatment was initiated with botulinum neurotoxin A complex (BoNT/A; 200 mouse units [MU] of Dysport; dilution, 500 MU per 2.5 mL; Ipsen Pharma GmbH, Ettlingen, Germany). It was her first contact with botulinum neurotoxins. For the second treatment 13 weeks later, dosage and injection protocol were modified (340 MU of Dysport), and an excellent control of symptoms was obtained (4 weeks after injection: Tsui score, 1; TWSTRS score, 2). The third and fourth treatments, which were identical to the second, had the same success (intervals of 12 and 14 weeks, . . . [Full Text of this Article]


Comment

Conclusions

AUTHOR INFORMATION
Sebastian Paus, MD; Hans Bigalke, MD; Thomas Klockgether, MD







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