This Article  • Full text  • PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Topic Collections  • Genetic Disorders  • Cerebrovascular Disease  • Neuromuscular diseases  • Neurology, Other  • Alert me on articles by topic

Arch Neurol. 2006;63:1653-1654.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

A 47-year-old Hispanic woman was found unresponsive by her family shortly after complaining of sudden onset of headache and vomiting. On initial neurologic examination she was deeply comatose with extensor posturing of all extremities. Findings from physical examination revealed multiple café au lait spots, numerous cutaneous neurofibromas, and axillary freckling (Figure, D) thereby meeting the diagnostic criteria for neurofibromatosis 1 (NF1). The patient's medical history was only remarkable for hypertension; the family history revealed 2 of 3 daughters with similar skin lesions. Computed tomography (CT) of the brain identified intraventricular and intraparenchymal hemorrhage with mass effects (Figure, A) as well as ischemic lesions mostly defined to the border zone distribution of the right anterior and middle cerebral arteries. Diagnostic 4-vessel and CT angiography outlined severe right-sided occlusive disease in the supraclinoid internal carotid, middle cerebral, and anterior cerebral arteries with marked leptomeningeal collateral vessels and neovascularization . . . [Full Text of this Article]

AUTHOR INFORMATION

Mohsin Khan, MD; Roberta L. Novakovic, MD; Axel J. Rosengart, MD, PhD