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edited by John V. Bowler, MD, FRCP, and Vladimir Hachinski, MD, FRCP, DSc, 368 pp, with illus, $125, ISBN 0-19-263267-1, Oxford, England, Oxford University Press, 2003.

Arch Neurol. 2005;62:831-832.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

The notion that cerebrovascular disease can cause severe cognitive deficits has been recognized in literature for several centuries. However, the diagnosis of vascular dementia (VaD) is still problematic; this issue is addressed very well in this book. The first and last chapters by Drs Bowler and Hachinski provide a clear insight of the current problems in the clinical diagnosis of VaD and set the framework for future research.

At the center of the debate about fundamental problems in the diagnosis of VaD is the current definition of dementia. The majority of the criteria for dementia are based on the assumption that memory is impaired. This Alzheimer-like definition of dementia precluded the identification of VaD patients with cognitive deficits outside the memory domains. The heterogeneity of the vascular lesions (eg, single ischemic lesion, multiple lesions, hemorrhagic lesions, leukoaraiosis), and the concomitant manifestation of Alzheimer disease and cerebrovascular disease are 2 additional . . . [Full Text of this Article]

AUTHOR INFORMATION

Oscar L. Lopez, MD, Reviewer

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