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  Vol. 62 No. 10, October 2005 TABLE OF CONTENTS
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Multisite Randomized Trial of Deep Brain Stimulation

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

The recent article by Anderson et al1 and the accompanying editorial by Okun and Foote2 regarding pallidal vs subthalamic nucleus deep brain stimulation (DBS) for Parkinson disease underscores the need for further research to establish the long-term benefits and potential risks of these treatment approaches. The Department of Veterans Affairs Cooperative Studies Program (Washington, DC), in collaboration with the National Institute of Neurological Disorders and Stroke (Bethesda, Md) and the DBS device manufacturer Medtronic (Minneapolis, Minn), has launched a multicenter, randomized trial of bilateral DBS of the globus pallidus vs subthalamic nucleus in persons with Parkinson disease. This landmark study involving 6 Department of Veterans Affairs Parkinson’s Disease Research, Education, and Clinical Centers and their university affiliates is well under way; 232 patients are enrolled toward the final cohort of 316. All sites have recognized expertise with medical and surgical treatment of Parkinson disease, including experience with globus pallidus and . . . [Full Text of this Article]

AUTHOR INFORMATION

Kenneth Follett, MD, PhD; Frances Weaver, PhD; Matthew Stern, MD; William Marks, MD; Penelope Hogarth, MD; Katherine Holloway, MD; Jeff Bronstein, MD; John Duda, MD; Stacy Horn, DO; Eugene Lai, MD; Ali Samii, MD



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RELATED ARTICLES

Multisite Randomized Trial of Deep Brain Stimulation—Reply
Michael S. Okun and Kelly D. Foote
Arch Neurol. 2005;62(10):1644-1645.
EXTRACT | FULL TEXT  

Subthalamic Nucleus vs Globus Pallidus Interna Deep Brain Stimulation, the Rematch: Will Pallidal Deep Brain Stimulation Make a Triumphant Return?
Michael S. Okun and Kelly D. Foote
Arch Neurol. 2005;62(4):533-536.
EXTRACT | FULL TEXT  

Pallidal vs Subthalamic Nucleus Deep Brain Stimulation in Parkinson Disease
Valerie C. Anderson, Kim J. Burchiel, Penelope Hogarth, Jacques Favre, and John P. Hammerstad
Arch Neurol. 2005;62(4):554-560.
ABSTRACT | FULL TEXT  






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