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	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

The delightfully illustrated and timely editorial¹ on the "rematch" between globus pallidus interna (GPi) and subthalamic nucleus (STN) deep brain stimulation (DBS) in Parkinson disease was of special interest to our group, which just published a further contribution on this issue based on a nonrandomized study.² The confirmation by Anderson and colleagues,³ in the only randomized, blinded comparative study to date, that STN and GPi DBS are equally effective in relieving motor symptoms and levodopa-induced dyskinesia at 1 year challenges the widely held assumption that STN is a superior target. They observed greater improvements in bradykinesia and higher levodopa dose reduction in their STN group but without significance (P>.05). These results require confirmation in wider studies over a longer term.

In an open study with similar sample size and follow-up, we also found no differences in main clinical variables between targets, although the greater percentage reduction of levodopa . . . [Full Text of this Article]

AUTHOR INFORMATION

Adolfo Minguez-Castellanos, MD, PhD; Francisco Escamilla-Sevilla, MD, PhD

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