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In reply

We thank both Mitchell et al and Janssens et al for their interest in our article.¹ We would like to draw their attention to another recently published paper in Neurology² on this same cohort and not referenced in this article (submitted at the same time as this manuscript to Archives of Neurology). This describes the levels of impairment, disability, and handicap and adds objective and physician-measured information rather than the subjective patient self-reporting as in this Archives paper.

Mitchell et al make valid points regarding the validity of using medical records to determine QOL. We apologize for any confusion, but all 185 patients filled out the questionnaire (172 of 178 interviewed in person [6 excluded because of dementia] and 13 answered the questionnaire over the telephone, with 1 refusing). The 9 patients that refused the interview had their medical records reviewed and Expanded Disability Status Scale score was . . . [Full Text of this Article]

AUTHOR INFORMATION

Sean J. Pittock, MD; Robyn L. McClelland, PhD; Moses Rodriguez, MD

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