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History of Dermatomyositis
Todd D. Levine, MD
Arch Neurol. 2003;60:780-782.
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INTRODUCTION
Although Wagner1 and Unverricht2 are credited with the first descriptions of dermatomyositis in the late 1880s, Unverricht suggested that Virchow3 may have been the first one to recognize the clinical features of this disease: "It is interesting that Virchow, already in the year 1866 . . . observed a patient he described as spotted with a rash and who otherwise reminded him of polymyositis."
Wagner1 also recognized an association between the rash and muscle weakness, but "was bent to incorporate the affection into the group of diseases of polymyositis and regarded it to a certain extent as the acutest form of the disease," not as a unique entity. It was not until Unverricht's seminal article in 18912 that the concept of an intimate connection between the rash and the muscle weakness became generally accepted and dermatomyositis and polymyositis became 2 distinct diseases.
With regards to the . . . [Full Text of this Article]
ETIOLOGY
CLINICAL DIAGNOSIS
PARANEOPLASTIC THEORIES
MUSCLE BIOPSY
THERAPY
From the Phoenix Neurological Associates and Department of Neurology, University of Arizona, Phoenix.
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