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Kupersmith et al¹ report that corticosteroid treatment for patients with ocular myasthenia gravis may significantly reduce the development of generalized myasthenia gravis at 2 years. In their article, the Figure showing the Kaplan-Meier curves of the cumulative development of ocular to generalized myasthenia gravis has some inaccuracies. The treated group should be the lower curve, as a dashed line, and the untreated group should be the upper one, as a solid line. The lower curve also seems to have some mistakes in scale: the 2 curves get closer and closer, whereas the follow-up period becomes longer than 2 years and finally 6 years according to the Figure. The longest period of follow-up was actually 16 years. If the authors extend the cumulative curves to more than 6 years, perhaps the 2 lines will meet. In that case, corticosteroid treatment would just delay the development of generalized myasthenia gravis for several . . . [Full Text of this Article]

Huei-Shyong Wang, MD
Taoyuan, Taiwan

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