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A Few Corrections to Our Article
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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We regret the following errors in our ARCHIVES publication.1 Part of our article described the analysis of a
polymorphism of the dopamine D4 receptor (DRD4) gene
among subjects with Alzheimer disease (AD). We incorrectly referenced the
published assay used by one of the coauthors (V.L.N.). The assays actually
involved another method.2
Recently, we noted significant differences in the frequency of DRD4 long (DRD4L) alleles among
our subjects compared with published figures for normal controls.3-5 This prompted
us to re-assay DRD4 genotypes among available DNA
samples from the original cohort (n = 213) and an additional sample of AD
subjects (n = 202), using a minor modification of a published method (details
available from R.A.S.).6 These assays were
conducted in another coauthor's laboratory (M.I.K.). The DRD4L frequency estimates from the assays using this method were significantly
lower than the estimates found using the initial assays. The DRD4 . . . [Full Text of this Article]
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