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Therapies for Movement Disorders
Arch Neurol. 2002;59:699-702.
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ADVANCES IN neurophysiology, pharmacology, surgical technology, and
molecular biology have provided the basis for contemporary therapies (Table 1) for movement disorders. This article
will focus on the treatment of 4 conditions commonly seen in a movement disorder
practice: Parkinson disease (PD), dystonia, essential tremor, and tic disorders.
Table appears in full text version.
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Commonly Used Oral Drugs for Movement Disorders
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PARKINSON DISEASE
Symptomatic therapy for patients with early signs of PD is generally
delayed until there is functional impairment.1
In the meantime, the issue of putative neuroprotection can be addressed with
the patient. So far, there is no medication that has been unequivocally proven
to halt or slow disease progression. Research on new potential neuroprotective
agents is ongoing, and antiapoptotic agents, antioxidants, and drugs that
interrupt the excitotoxic cascade are currently under study. Facilitating
access to study centers for participation in clinical trials is an important
intervention for interested subjects. The Parkinson Study Group is a . . . [Full Text of this Article] DYSTONIA
ESSENTIAL TREMOR
TIC DISORDERS
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