This Article  • Full text  • PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on ISI (1)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Topic Collections  • Gastrointestinal Diseases  • History of Medicine  • Nutritional and Metabolic Disorders  • Malabsorption Syndromes  • Alert me on articles by topic

Adi Vaknin-Dembinsky, MD; Rami Eliakim, MD; Israel Steiner, MD

Arch Neurol. 2002;59:647-648.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

INTRODUCTION

Celiac disease (CD) is an autoimmune enteropathy triggered by the ingestion of gluten in genetically susceptible individuals.¹ Developments in the understanding of the pathogenetic basis of the disease and the introduction of serological diagnostic markers have enabled the delineation of its epidemiological features and its clinical spectrum. This, in turn, has led to increased interest in the possible neurological manifestations and involvement in patients with this disorder.

CLINICAL DESCRIPTIONS

Celiac disease is clinically characterized by a malabsorption syndrome, weight loss, abdominal distention, diarrhea, steatorrhea, malaise, iron deficiency anemia, and bone disease. Most of these features were already noted in the first description of the disorder, dated 200 AD:

The stomach being the digestive organ, labors in digestion when diarrhea seizes the patient. If this diarrhea does not proceed from a slight cause of only one or two days' duration, and if, in addition, . . . [Full Text of this Article]