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Harvey Cushing and Medulloblastoma
Lara J. Kunschner, MD
Arch Neurol. 2002;59:642-645.
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INTRODUCTION
History is in essence the telling of a story. The story of our current
understanding of medulloblastoma, or cerebellar primitive neuroectodermal
tumor, as it is now known, begins with the formidable and exhaustive work
of Harvey Cushing, MD (1869-1939). The first recorded foray into the treatment
of brain tumors in the United States began in 1888 with the resection of a
meningioma by William W. Keen. Surgery at the time was greatly hampered by
several conditions that limited the physician encountering a patient suspected
of harboring a brain tumor. Little if any progress beyond that of pre-Columbian
trepanation was made with regards to neurosurgery until the entry of Cushing
into the surgical theaters of The Johns Hopkins Hospital in Baltimore, Md,
and later Peter Bent Brigham Hospital in Boston, Mass. As Matson and German1 wrote in his biography: "Cushing lived at a time when
medicine and . . . [Full Text of this Article]
CLASSIFICATION OF BRAIN TUMORS
MEDULLOBLASTOMA AS A DISTINCT ENTITY
CLINICAL FEATURES
SURGICAL TREATMENT
RADIOTHERAPY
From the Department of Neurology, Allegheny General Hospital, Pittsburgh,
Pa.
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