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David E. J. Linden, MD, DPhil (Oxon)

Arch Neurol. 2002;59:308-313.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

INTRODUCTION

Making accurate visual representations of the structure of the human brain has been one of the most challenging tasks of anatomical research for the past 500 years. Already, the illustrations of the brain in the De Humani Corporis Fabrica, by Andreas Vesalius, and Thomas Willis' Cerebri Anatome display an often astonishing quality (Figure 1, Figure 2, and Figure 3).^1-2 In the 19th and early 20th centuries, the combination of microscopic and macroscopic techniques yielded an ever-increasing knowledge about the connectivity of the central nervous system, culminating in the myelogenetic method of Flechsig and the cytoarchitectonic maps of the cerebral cortex by Brodmann (Figure 4 and Figure 5).² At the same time, lesion data and direct electrical stimulation of the cortex formed the basis of functional maps of the primate brain (Figure 6).³ The development of . . . [Full Text of this Article]

THE VENTRICLES

WHITE MATTER AND CORTEX

CONVOLUTIONS OF THE BRAIN AND THE GYRAL PATTERN

From the Departments of Neurology and Psychiatry, Johann Wolfgang Goethe-Universität, and the Max Planck Institute for Brain Research, Frankfurt am Main, Germany.