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Juvenile Myoclonic Epilepsy
Pierre Genton, MD;
Philippe Gelisse, MD
Arch Neurol. 2001;58:1487-1490.
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INTRODUCTION
As one of the most common types of idiopathic epilepsies, juvenile myoclonic
epilepsy (JME) has been the subject of intensive research, which culminated
in a comprehensive monograph,1 published in
honor of Prof Dieter Janz, after whom the condition is often named. This condition
was finally established as an epileptic syndrome in 1989,2
with the following definition:
Juvenile myoclonic epilepsy appears around puberty and is characterized
by seizures with bilateral, single or repetitive, arrhythmic, irregular myoclonic
jerks, predominantly in the arms. Jerks may cause some patients to fall suddenly.
No disturbance of consciousness is noticeable. The disorder may be inherited,
and sex distribution is equal. Often, there are generalized tonic-clonic seizures
and, less often, infrequent absences. The seizures usually occur shortly after
awakening and are often precipitated by sleep deprivation. Interictal and
ictal EEGs [electroencephalograms] have rapid, generalized, often irregular
spike-waves and polyspike-waves; there is . . . [Full Text of this Article]
PREHISTORY OF JME
DESCRIPTION OF JME
SLOW INTERNATIONAL RECOGNITION
RECENT ADVANCES AND OPEN QUESTIONS
From the Centre Saint Paul, Marseille, France (Dr Genton); and Department
of Neurophysiology and Epileptology, Gui de Chauliac Hospital, Montpellier,
France (Dr Gelisse).
Corresponding author and reprints: Pierre Genton, MD, Centre Saint
Paul, 300 Blvd de Sainte Marguerite, 13258 Marseille 09, France (e-mail: piergen@aol.com).
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