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Triptans for Migraine Headache: Therapeutic Progress Meets a Heterogeneous Patient Response
John N. Whitaker, MD
Birmingham, Ala
Arch Neurol. 2001;58:1482-1483.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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MIGRAINE IS a common, painful, and often disabling condition with major
social, financial, and personal ramifications. Over the past decade, there
have been major advancements in the treatment of migraine, most notably in
the recognition of effective therapy that targets the vascular serotonin receptors
of the 5-HT1B and 5HT1D types and the array of present
and future triptans that serve as agonists in reacting with those receptors.
The care of patients with migraine involves many approaches, but the triptans
serve as one of the most effective and frequently used abortives for headache
from which sufferers need and demand prompt and effective relief.
A rationale for choosing among the triptans is often unclear, leaving
the treating physician with ambivalence as to which among the highly marketed
drugs in the competitive pharmaceutical marketplace should be selected. As
clearly indicated in position papers prepared by experts in the field . . . [Full Text of this Article]
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