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Tuma and DeAngelis¹ report that delirium in patients with cancer may have multiple causes, many of which are reversible and allow a complete recovery of cognitive functions. They underscore the importance of neuroimaging investigations even in the absence of focal neurological signs, but overlook the usefulness of the electroencephalogram (EEG) in such patients. We feel that an EEG should be performed as well, because it can identify patients with nonconvulsive status epilepticus (NCSE), whose mental state may mimic delirium.^2-3

Over the last 2 years, we have studied 305 consecutive patients with cancer who underwent neurological consultation while hospitalized in the internal medicine departments of an academic hospital. Terminally ill patients were not considered in the study. Altered mental status (coma or delirium) was observed in 84 patients (28%). Brain metastases were responsible in 32 patients (38%). Underlying diseases were lymphoma or leukemia (n = 25 [30%]), lung cancer (n = . . . [Full Text of this Article]

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