This Article  • Full text  • PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Contact me when this article is cited  Related Content  • Similar articles in this journal

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Arecent article describing the findings by Khoury et al¹ correlating T cell markers with clinical status and MRI findings in patients with MS is interesting but the results cannot be translated into long-term follow-up criteria since T-cell changes were transitory. It would be important to know if the authors encountered patients with confounding results, eg, those who had no MRI changes but had an increased percentage of cells expressing interleukin-2 receptor (CD25), class II major histocompatability complex, or surface dipeptidyl peptidase (CD26). This could be important since another study² found that the levels of sICAM-1, a molecule of the immunoglobulin superfamily, were elevated without gadolinium enhancement on MRI. That Khoury et al¹ found that MRI results and T-cell markers were not congruent in some patients implies that routine MRI with gadolinium enhancement may have to be supplemented with other laboratory tests and that, in some subtypes of MS, no radiological . . . [Full Text of this Article]