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Patterns on Cranial Magnetic Resonance Imaging in Elderly People and Vascular Disease Outcomes
Arch Neurol. 2001;58:2074.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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In a previous article, we used a statistical technique called cluster analysis to define 5 groups of elderly participants in the Cardiovascular Health Study (CHS)1 based on the pattern of findings on cranial magnetic resonance imaging (MRI). We labeled the clusters as follows: normal, atrophy, leukoaraiosis, simple infarct, and complex infarct. These clusters differed with respect to vascular risk factor profiles.
We have now examined the relation between the cluster variable and a variety of outcomes that are monitored in the CHS. Table 1 provides the percentage of participants experiencing an incident event in each cluster in the 5.3 years following the MRI. Incident events were 3 to 4 times more common in the complex infarct cluster, combining brain infarcts with prominent white matter changes, than in the normal cluster for all outcomes except angina and myocardial infarction. The percentage of participants experiencing an incident stroke was higher in the . . . [Full Text of this Article]
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