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Benefits and Limitations of Ablation, Stimulation, Restoration, and Radiation

Arch Neurol. 2001;58:1970-1972.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

RENEWED INTEREST in the surgical treatment of Parkinson disease (PD), essential tremor (ET), and other movement disorders has been fueled by an improved understanding of the functional anatomy of the basal ganglia and their connections; refinements of methods and techniques in neurosurgery, neurophysiology, and neuroimaging; and the emergence of complications from chronic medical therapy.¹ Because of an increased awareness of surgical options for patients with PD, the attitudes of physicians toward referring patients for surgery have been changing. In one survey, 94.3% of neurologists considered referring their patients with PD for surgery.²

Besides surgical peripheral denervation, used primarily in medically intractable patients with focal dystonia, 4 central stereotactic approaches are currently used in the treatment of PD, ET, and other movement disorders: (1) ablative procedures (eg, thalamotomy, pallidotomy, and subthalamotomy); (2) deep brain stimulation (DBS); (3) attempts to restore degenerated tissue with brain grafting; and (4) focal radiation with a . . . [Full Text of this Article]

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