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Genomic Neurology: A New Beginning
Arch Neurol. 2001;58:1739-1741.
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A PARADIGM SHIFT in the conceptualization of neurogenetics occurred
on June 26, 2000, when the initial sequencing of the human genome was announced
by Francis Collins, Director of the Human Genome Project of the National Institutes
of Health, and J. Craig Venter of Celera Genomics. The press conference for
this momentous announcement was held at the White House and was sponsored
jointly by then-President Bill Clinton and Prime Minister Tony Blair in London,
linked by satellite. On February 15, 2001, the International Human Genome
Sequencing Consortium (led by Collins), and on February 16, 2001, the Celera
Genomics Group (led by Venter), published their respective initial sequences
of the human genome.1, 2 Both groups
reported that the number of protein-encoding transcripts, or genes, in the
human genome is about 30 000—far less than previously predicted.
DNA was sequenced from 5 individuals: 3 males and 2 females, including 1 of
African, 1 of Chinese, . . . [Full Text of this Article]
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