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Leukoaraiosis
Reifying Rarefaction
Arch Neurol. 2000;57:925-926.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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MEDICAL TERMS sometimes acquire a life of their own. The term leukoaraiosis (LA) was coined to avoid presumptions about etiology and neuropathology of a radiological phenomenon—white matter rarefaction found first on computed tomographic scans and later more profusely on magnetic resonance images.1 It was to be a
neutral term, exact enough to define white matter changes in the elderly or the demented, general enough that it serves as a description and a label, and demanding enough that it calls for a precise clinical and imaging description accompanied when possible by pathologic confirmation.1
The intention was that as the significance of the lesions became clear, a more precise and clinically relevant nomenclature would be developed. However, the term has gained acceptance as an entity, the concept having been undeservedly reified.
This is reflected in the contradictory nature of several reports in the abundant literature related to white matter changes (WMCs) that . . . [Full Text of this Article]
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