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  Vol. 57 No. 7, July 2000 TABLE OF CONTENTS
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  Controversies in Neurology
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 •Multiple Sclerosis/ Demyelinating Disease
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Trauma Does Not Precipitate Multiple Sclerosis

Stuart D. Cook, MD

Arch Neurol. 2000;57:1077-1078.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

THE ROLE of trauma in causing or aggravating multiple sclerosis (MS) has been intensely debated in the medical literature as well as in the courtroom for many years. In an attempt to develop a consensus opinion on this issue, the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology critically reviewed relevant published data on the possible effects of trauma on MS. In an article published in 1999,1 the subcommittee stated,

On the basis of strong and generally consistent Class II evidence, any posited association of trauma, especially head trauma, with more than a small effect on either MS onset or MS exacerbation is excluded. Moreover, the preponderance of Class II evidence supports no association between physical trauma and either MS onset or exacerbation.

My review of the pertinent literature led me to a similar, if not identical, conclusion.

TRAUMA AND MS CAUSATION

Multiple sclerosis is generally considered . . . [Full Text of this Article]


TRAUMA AND EXACERBATIONS OR DISEASE PROGRESSION

CONCLUSIONS
From the Department of Neurosciences, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark.


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Arch Neurol. 2000;57(7):1074-1077.
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Trauma and Multiple Sclerosis
Vladimir Hachinski
Arch Neurol. 2000;57(7):1078.
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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Axonal Injury Heralds Virus-Induced Demyelination
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