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Arch Neurol. 2000;57:749.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

A 44-YEAR-OLD right-handed woman had a 4-year history of simple partial seizures (focal motor activity involving the left side of the face and mouth) and rare secondary generalized tonic-clonic seizures associated with a right frontal lobe mass. After 4 years, the slowly enlarging lesion led to patient referral to us for evaluation. Taking antiepileptics, she had no generalized seizures but several partial seizures per month. Routine magnetic resonance imaging (MRI) (Figure 1, A) revealed a nonenhancing lesion of the right frontal lobe. Blood-oxygen level–dependent functional MRI during left wrist flexion was localized (Figure 1, B). Functional MRI reveals disproportionate changes in blood flow related to oxygen use in response to neocortical activation. An increase in blood flow increases the amount of deoxygenated (paramagnetic) hemoglobin, leading to higher MRI signals from the activated tissue. Concern that the tumor might be adjacent to or involve motor cortex led . . . [Full Text of this Article]

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