This Article  • Full text  • PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on HighWire  • Citing articles on ISI (4)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Topic Collections  • Neurology, Other  • Alert me on articles by topic

Arch Neurol. 2000;57:587-588.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

A 60-YEAR-OLD woman presented with a 10-year history of gradual enlargement of her hands and feet and progressive acromegalic changes of her face (Figure 1). Six months prior to presentation, she suffered from persistent frontal headaches. She had neither visual field defects nor papilledema. Growth hormone (GH) serum concentrations were increased (31.6 mU/L; normal, <10 mU/L). Serum levels of the other pituitary hormones were normal. Neuroimaging showed a large intrasellar tumor (Figure 2), which was almost completely removed via a transsphenoidal approach. The postoperative course was uneventful. Findings from neuropathological evaluation revealed a mixture of 2 different tumor tissues: a GH-producing adenoma and a benign ganglion cell tumor with dysplastic and occasionally binucleated ganglion cells in a neuropil-like matrix (Figure 3). The histological diagnosis was mixed gangliocytoma/GH-producing adenoma.

Figure appears in full text version. Figure 1. The patient showed marked acromegalic changes that included macroglossia.

Figure appears in full text version. Figure 2. Frontal T1-weighted magnetic . . . [Full Text of this Article]

COMMENT

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Pituitary Gangliocytoma-Adenoma Presenting With Acromegaly: Response to Treatment
Luna et al.
Arch Intern Med 2001;161:1010-1011.
FULL TEXT